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![Surgical management of cholangiocarcinoma](https://image.oaes.cc/1c1dc98b-7469-48fd-b35f-94540841f59c/4409.fig.1.jpg)
Figure 1. Cholangiocarcinoma classification includes intrahepatic, hilar, and extrahepatic or distal subgroups. The majority of cholangiocarcinomas arise from perihilar or distal ducts, while less than 10% are from intrahepatic ducts. Additionally, through improved genetic analysis, there is a better understanding of the shared and distinct somatic genomic landscapes of cholangiocarcinoma and possible actionable mutation for which therapies may exist.