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![Contrast-enhanced ultrasonography with Sonazoid in hepatocellular carcinoma diagnosis](https://image.oaes.cc/4deea99a-ae31-4cd8-a6ca-4c3358ce5950/3579.fig.2.jpg)
Figure 2. Behavior of microbubbles exposed to ultrasound. Microbubbles oscillate in a symmetrical manner at very low MI (< 0.1) with stable linear scattering. In contrast, asymmetrical oscillations are observed at low/medium MI (0.2-0.6), with microbubbles expanding more than they contract because they are more resistant to compression. This asymmetry causes harmonic emissions. Transient non-linear scattering occurs at high MI (> 0.6), and is followed by microbubble destruction. MI: mechanical index