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![Liver regeneration: metabolic and epigenetic regulation](https://image.oaes.cc/251ca2fa-7d20-409a-8697-c1a1619f6681/3896.fig.2.jpg)
Figure 2. Hepatic insufficiency caused by surgical or toxin-induced injury induces metabolic alterations and epigenetic changes in the liver. Besides the isolated metabolic and epigenetic regulation of hepatocyte proliferation and regeneration, a well-controlled interplay between metabolism and epigenetics controls liver regeneration events