fig1
From: Recent advances regarding tumor microenvironment and immunotherapy in hepatocellular carcinoma
Figure 1. HCC microenvironment components and linkage. A variety of immune-related cells in the tumor microenvironment can promote or inhibit the development of hepatocellular carcinoma through various mechanisms. HCC: hepatocellular carcinoma; VEGF: vascular endothelial growth factor; NK: natural killer; DC: dendritic cell; PDGF: platelet-derived growth factor; TGF: transforming growth factor; HGF: hepatocyte growth factor; EGF: epidermal growth factor; FGF: fibroblast growth factor; MPPs: matrix metalloproteinases; NO: nitric oxide; TNF: tumor necrosis factor; NKT: natural killer T cells; ROS: reactive oxygen species
