fig4
From: Hepatocellular carcinoma in alcoholic liver disease: mechanistic considerations and clinical facts
![Hepatocellular carcinoma in alcoholic liver disease: mechanistic considerations and clinical facts](https://image.oaes.cc/8b802d37-4e3b-4bce-a663-01c72f8d9231/3258.fig.4.jpg)
Figure 4. Hepatic microsomal cytochrome P450 and its interaction with substrates. Cytochrome P450 catalyzes the oxidation of substrates such as drugs and ethanol, which bind to the ferric (3+) iron of the cytochrome P450 as the initial metabolic step leading finally to the oxidized substrate. The original figure was published in and derived from a recent article[15]