fig1

Figure 1. Gene-based SNPs associated with HCC in the antigen processing and presentation pathway. The genes and their relationships obtained from KEGG’s antigen processing and presentation pathway. Purple boxes with white letters indicate genes SNP variations associated with HCC from the PoDA stepdown analysis. Removal of these loci reduced the overall threshold of significance below that observed for the entire pathway. Genes in open boxes (with orange letters) indicate gens which could be removed without altering significance of the pathway’s association. HCC: hepatocellular carcinoma