fig1
![Hypoxic microenvironment and hepatocellular carcinoma treatment](https://image.oaes.cc/f344564c-5d9a-40eb-a597-c3fee08a744f/2643.fig.1.png)
Figure 1. Molecular pathways involved in hypoxia HCC malignance. HCC: hepatocellular carcinoma; YAP: Yes associate-protein; MMPs: matrix metalloproteinases; HMGB1: high mobility group box 1; TLR: Toll-like receptor; IL: interleukin; VEGF: vascular endothelial growth factor; HIF: hypoxia-induced factor; SCF: stem cell factor