fig4

Figure 4. A case of HCC development after DAA treatment. A 81-year-old male. Before the start of DAA treatment, TACE was performed twice. Then, DAA treatment was initiated after a complete response was achieved. CE-CT after 3 months from the end of DAA treatment showed local and distant HCC recurrence. CHA angiography showed multiple HCC. Thus, a 3rd TACE was performed for HCC recurrence. HCC: hepatocellular carcinoma; DAA: direct-acting antiviral; TACE: transarterial chemoembolization; CT: computed tomography; SOF: sofosbuvir; LDV: ledipasvir; ALT: alanine aminotransferase; AFP: alpha-fetoprotein; HCV: hepatic C virus; SVR: sustained virological response