fig1

Figure 1. Diagram of the percutaneous hepatic perfusion system. This Delcath^® Catheter System is used to infuse melphalan into the hepatic artery percutaneously (syringe) via the femoral artery. A double balloon catheter (shown in the upper right) is placed in the retro-hepatic inferior vena cava under fluoroscopic guidance (middle right image) to isolate the hepatic venous outflow. The multiple fenestrations along the balloon catheter then draw out the isolated blood which then is directed into the extracorporeal system. The blood is then pumped thorough a pair of activated charcoal filters, which extract the melphalan, before being returned to the systemic circulation. (This image has been reproduced with permission and purchase from The Cancer Journal)