fig3

Figure 3. A photomicrograph of liver section of (a) control rat showing normal structure of hepatic lobule, central vein, and blood sinusoid(s); (b) rat fed FB₁-contaminated diet showing vacuolar degeneration, hepatocellular necrosis, and congestion of blood sinusoids which are surrounded by aggregation of inflammatory cells, proliferation and dilation of bile duct, and signs of fibrosis; (c) rat treated with JELD showing normal hepatocytes architecture and dilation of sinusoid; (d) rat treated with JEHD showing no pathological changes; (e) rat fed FB₁-contaminated diet and treated with JELD showing marked improvement in histological features of hepatocyte tissue with minimal vacuolar degeneration still present; and (f) rat fed FB₁-contaminated diet and treated with JEHD showing histological features resembling that of normal hepatocytes (a, e, f: HE, ×200; b, c, d: HE, ×400). FB₁: fumonisin B₁; JELD: low dose of jojoba seed extract; JEHD: high dose of jojoba seed extract