fig6

Knockdown of the <i>EEF1A2</i> gene reduces lung cancer brain metastasis by downregulating the <i>BCL10/NFκB</i> pathway

Figure 6. Increased expression of EEF1A2, BCL10 and phosphorylated NFκB in the LCBM. (A) RT-qPCR was used to determine the relative expression levels of EEF1A2, Cdc42, and E-cadherin genes in samples from 21 patients with LCBM and 21 patients with LC. *P < 0.05; ***P < 0.001; ns indicates no significant difference compared to the LC group. (B and C) Western blot analysis of EEF1A2, BCL10, and phosphorylated NFκB (phospho-NFκB) in tumor samples from five LC patients and five LCBM patients. *P < 0.05; ***P < 0.001; ****P < 0.0001.

Journal of Cancer Metastasis and Treatment
ISSN 2454-2857 (Online) 2394-4722 (Print)

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