fig5
From: The role of PD-1/PD-L1 signaling pathway in cancer pathogenesis and treatment: a systematic review
![The role of PD-1/PD-L1 signaling pathway in cancer pathogenesis and treatment: a systematic review](https://image.oaes.cc/93aa07ff-f1ea-4b89-8376-e10ad2a0561c/jcmt4015.fig.5.jpg)
Figure 5. Basic oncogenic pathways in melanoma. BRAF mutations are mostly common and, in the end, lead to the expression of PD-L1. The PI3K pathway is usually activated simultaneously and is inhibited by PTEN.