fig10
From: The role of PD-1/PD-L1 signaling pathway in cancer pathogenesis and treatment: a systematic review
Figure 10. Aspirin inhibits both COX-1 and COX-2. Arachidonic acid makes PGH2 with the help of COX-1 and COX-2. The following derivatives of PGH2 bind to their receptors and induce their specific effects.