fig8
Figure 8. The MALDI technique is based on a series of matrix substances surrounding the particles to be detected, after which the laser irradiates the detection plane, and the matrix-wrapped particles to be seen are desorbed from the overall material. Then, the particles to be seen and the surrounding matrix particles undergo desolvation and ionization, whereby the matrix substances transfer positive charges to the particles to be caught to form a Particle for Mass Spectrometry.