fig5
Figure 5. Lipid-based NPs have flexible surface modification options, including cell coating, Vitamin, etc.; they can also change the surface toughness to suit different drug delivery needs for lipid-based. Meanwhile, lipid-based NPs can receive intrinsic or extrinsic stimuli to produce a response (usually rupture), with intrinsic motivations including various enzyme levels, metabolic changes, and other precision regulation, and extrinsic stimuli including physical stimuli such as sound, light, and electricity.