fig4

Some synergetic therapy strategies for overcoming hypoxia for photodynamic therapy of cancer

Figure 4. (A) C-m-ABs displays Photo-Fenton-like activity in the schematic illustration; (B) An 8-min reaction time was used to deplete DPBF after undergoing different treatments; (C) The viability of MGC-803 cells was analyzed using C-m-ABs containing different levels of DOX at pH 7.4 or 5.0 for 12 h; (D) Cell viability of MGC-803 cells treated with C-m-ABs (no DOX) and ICG under laser irradiation (1.0 W cm-2 or 1.4 W cm-2); (E) To test MGC-803 cell viability, C-m-ABs and DOX + ICG were employed, respectively, under laser irradiation (1.0 W cm-2 or 1.4 W cm-2); (F) Visual images of excised tumor at 15 day after treated with DOX, DOX + ICG + laser (1.4 W cm-2), C-m-ABs, C-m-Abs + laser (1.0 W cm-2) (PDT group), and C-m-ABs+laser (1.4 W cm-2, PDT/PTT group); (G) Curves of relative tumor volume fluctuation over time. Reprinted from ref.[104] with permission. Copyright 2019, Wiley-VCH.

Journal of Cancer Metastasis and Treatment
ISSN 2454-2857 (Online) 2394-4722 (Print)

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