fig4

Figure 4. NETs participate in the cascade process of tumor metastasis. NETs induce EMT of tumor cells and enhance the migration ability. NETs trap tumor cells and protect them from CTLs and NK cells. NETs: neutrophil extracellular traps; ROS: reactive oxygen species; EMT: epithelial-mesenchymal transformation; CTLs: cytotoxic T lymphocytes; NK cells: natural killer cells; TGF-β: transforming growth factor. Created in BioRender.com.