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Figure 2. Neutrophils secreted ROS to inhibit NK cell function; TANs recruit phagocytes by secreting chemokines; Neutrophils suppress the T cell immunity by secreting MMPs, ROS, ARG1, and iNOS. IL-17 secreted by γδ-T cells promotes neutrophil recruitment. Neutrophils inhibit T cell function by expressing PD-L1, and some PD-L1 can be embedded in NETs. ROS: reactive oxygen species; MMPs: matrix metalloproteinase; Arg-1: arginase-1; iNOS: inducible nitric oxide synthase; NETs:neutrophil extracellular traps; PD-L1: programmed death ligand-1; TANs: tumor-associated neutrophils. Created in BioRender.com.