fig1
![The heterogeneity of CAFs and immune cell populations in the tumor microenvironment of pancreatic adenocarcinoma](https://image.oaes.cc/dd6689b6-7fcd-4221-b1c6-4bddb5a11752/5190.fig.1.jpg)
Figure 1. Origins (left) and differentiation (right) of cancer-associated fibroblasts. MSC: Mesenchymal stem cell; EndMt: endothelial-to-mesenchymal transition; EMT: epithelial-to-mesenchymal transition; MMT: mesenchymal-to-mesenchymal transition; CAF: cancer-associated fibroblast; myCAFs: myofibroblastic cancer-associated fibroblasts; iCAFs: inflammatory cancer-associated fibroblasts; apCAFs: antigen-presenting cancer-associated fibroblasts[8]. (Adopted from Herting et al., Cancer Metastasis Rev. 2021; doi:10.1007/s10555-021-09988-w).