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![Overcoming tumor antigen heterogeneity in <InlineParagraph>CAR-T cell</InlineParagraph> therapy for malignant mesothelioma (MM)](https://image.oaes.cc/fdc0c856-11c6-453a-b3b7-ca83dad56764/5065.fig.1.jpg)
Figure 1. The current therapeutic landscape of malignant pleural mesothelioma (MPM). A list of the first and second/third-line therapies in relation to their median overall survival (mOS). *FDA/EMA/NICE approval (for Nivolumab-Ipilimumab, FDA approval was granted in 2020, and EMA/NICE approval in 2021). Vin: Vinorelbine; Gem: gemcitabine.