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Figure 3. Overview of immune-related pathway maps and process networks in in vitro cocultures of A549 and PBMCs from three healthy donors, with (orange) and without (blue) treatment with human neutrophil peptide 1 (HNP1), after proteomic and MetaCoreTM analyses. A distinction is made between common pathway maps and process networks observed in all three healthy donors (A) and those observed in two out of three healthy donors (B). Significant differences (P ≤ 0.05) were retained after the Mann-Whitney U test, performed in R Software: P = 0.05 for all nine upregulated pathways for all three donors (A).
