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![Therapeutic targets in the pancreatic adenocarcinoma microenvironment: past challenges and opportunities for the future](https://image.oaes.cc/df0c55f8-8cb8-4e95-81c5-dc126727ad0e/4144.fig.1.jpg)
Figure 1. Schematic figure of the desmoplastic stromal reaction in PDAC involving fibroblasts, collagen, hyaluronic acid and extracellular matrix proteins (courtesy of Drs. A. Hosein, R. Brekken, and A. Maitra). PDAC: Pancreatic ductal adenocarcinoma.