fig2
![Targeting EZH2 for the treatment of soft tissue sarcomas](https://image.oaes.cc/7fffb25c-40ad-47b6-9465-b25a8e2f863b/3955.fig.2.jpg)
Figure 2. Histone methyltransferase activity of EZH2/PRC2 is part of a sequence of epigenetic alterations that lead to condensation of chromatin into tightly bound structures, thereby physically preventing access to transcription factors and other transcriptional machineries.