fig4
![Mouse tumor susceptibility genes identify drug combinations for multiple myeloma](https://image.oaes.cc/7a74ed76-0ad1-411d-8c09-4eb059ed1730/3567.fig.4.jpg)
Figure 4. Drug combinations involving mTOR and HDAC inhibitors have a cooperative effect leading to MYC protein degradation. Small molecules targeting the G-quadruplex structure in the MYC promoter inhibit MYC transcription. HDAC: histone deacetylase; mTOR: mechanistic target of rapamycin