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![Genetic characteristics and molecular diagnostics of bone tumors](https://image.oaes.cc/377a4309-21bc-4666-8d25-765aab053652/3898.fig.4.jpg)
Figure 4. FOS immunohistochemistry: immunohistochemistry for FOS shows nuclear positivity for the majority of the neoplastic tumor cells in osteoblastoma, this serves as a surrogate for the presence of FOS rearrangements, although it is not entirely specific (FOS immunohistochemistry, 20x magnification)