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![Autophagy and thyroid cancer](https://image.oaes.cc/e6650dca-d7b1-4081-890a-cfa11a305fdd/3878.fig.2.jpg)
Figure 2. Alterations in relative amounts of LC3-I and II by autophagy inducer and inhibitor in Western blotting. A reagent increases amounts of LC3-II in both upper and lower panels. However, a further increase in LC3-II by combination of the reagent and chloroquine indicate that the reagent is an autophagy inducer, but when the reagent is an inhibitor, amounts of LC3-II remains unchanged in combination of the reagent and chloroquine. LC3: light chain 3; CQ: chloroquine