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Figure 4. Relative expression of mRNA transcripts of PRR, ACE, ATIIR1 and ATIIR2 by NanoString mRNA analysis of four samples of metastatic melanoma to the brain showing high levels of expression of PRR, moderate levels for ACE, low levels for ATIIR1 and undetectable levels for ATIIR2, relative to the housekeeping gene GAPDH. PRR: pro-renin receptor; ATIIR1: angiotensin II receptor 1; ATIIR2: angiotensin II receptor 2; ACE: angiotensin converting enzyme