fig6

Figure 6. Different patterns of ADAMTS-1 and fibulin-1 expression in a breast cancer tissue array. Top: representative images of tissues used for the detection of ADAMTS-1 and fibulin-1 in different stages of breast carcinoma. Top two lines: fibulin-1 pattern at ×4 and ×20 magnifications. Bottom line: ADAMTS-1 pattern at ×4 magnification. Negative controls were performed by omitting primary antibodies. The intensity of fibulin-1 immunostaining is indicated as strong (+++), moderate (++), weak (+) or negative (-). Bottom: Kaplan-Meier overall survival plots for FBLN1, ADAMTS1 and FBLN1/ADAMTS1