fig3

Figure 3. Coexpression of ADAMTS-1 and fibulin-1 reduces the migration properties of the breast cancer cell line MCF-7 over type-I collagen and fibronectin. Top, Representative images of the migration of MCF-7 transfectants on wells coated with type-I collagen and fibronectin using the RadiusTM 24-Well Cell Migration Assay kit (Cell Biolabs). MCF-7 cells transfected with an empty vector were used as a control. Pictures of the initial (t: 0 h) and final (t: 24 h) times are included. The starting point is indicated with a thin dotted line, and the final point is indicated with a thick dotted line. Bottom, graphical representation of percentages of the area covered after 24 h (from three independent experiments)