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![Immunotherapy in colorectal cancer treatment: actual landscape and future perspectives](https://image.oaes.cc/ee54e2b2-3fe4-4314-9971-67220280eaa4/2868.fig.1.jpg)
Figure 1. Interactions between cancer cells and T-cells and the role of PD-1/PDL-1 and CTLA4. PD-1: programmed cell death-1; PDL-1: programmed cell death ligand-1; CTLA4: cytotoxic T-lymphocyte-associated protein 4; APC: antigen-presenting cell; MHC: major histocompatibility complexes