fig12
![Targeting autophagy with small molecules for cancer therapy](https://image.oaes.cc/e856c6ed-9778-45ec-9271-473028ff0eea/3046.fig.12.jpg)
Figure 12. 3D binding mode and interaction of PIK-III (PDB ID: 4PH4) (A), compound 3a (PDB ID: 5ENN) (B), compound 3c (PDB ID: 4UWF) (C) and compound 3f (PDB ID: 4UWL) (D) with Vps34. Hydrogen and water mediated hydrogen bonds are represented in black dotted lines