fig6
![Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention](https://image.oaes.cc/90c048c1-30a0-44b1-9c79-c69588a02257/2317.fig.6.png)
Figure 6. Close-up view of the AKR1C3 ligand-binding pocket. Illustrating the different compartments (the oxyanion site, the steroid channel and subpockets SP1, SP2 and SP3) that can be targeted with small molecules. NADP+ molecule is represented by a yellow square