fig12
![Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention](https://image.oaes.cc/90c048c1-30a0-44b1-9c79-c69588a02257/2317.fig.12.png)
Figure 12. Domain organisation of full length AR (FL-AR) and some AR splice variants (AR-Vs). The four functional domains are indicated as follows: the N-terminal domain (NTD, green rectangles), the DNA-binding domain (DBD, red circles); ligand-binding domain (LBD, blue rectangles) and the "hinge region", separating the LBD from the DBD (black lines). For AR-Vs lacking the LBD and/or the hinge region, the amino acids outside the previously described domains are listed. AR: androgen receptor