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Figure 3. The effect of Papaya seeds extract on non-cancerous undifferentiated 3T3L1 fibroblasts. Cells (10,000/well) were incubated with different concentration of water (A), methanol (B), and hexane (C) extracts of papaya white or black seeds in a CO₂ incubator at 37 ℃ for 24 h. After treatment, cell viability was determined using a WST-1 assay. Results are expressed as mean ± SD for at least 3 replicates. *Significant differences between treated and untreated groups were reported as *P < 0.05