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![Insights into mechanisms of tumor dissemination from circulating tumor cell lines of small cell lung cancer](https://image.oaes.cc/00a1cb99-313f-4e11-82e6-40a0a42ce71a/1768.fig.1.png)
Figure 1. Cell physiologic conditions in an SCLC CTC tumorosphere. This figure shows a microscopic image of a SCLC CTC BHGc10 tumorosphere with a schematic overlay indicating regions of proliferating, quiescent and hypoxic cells. These spheroid structures grow up to diameters of 1-2 millimeters and develop gradients of nutrient and oxygen supply as well as accumulation of metabolic waste products. SCLC: small cell lung cancer; CTC: circulating tumor cell