fig8

Figure 8. Effect of WS on expression of CCL2 in MDA-MB-231 xenografted tumors. (a and b, ×20) Hematoxylin and eosin sections of untreated and WS treated tumors, respectively; (c and d, ×20) immunohistochemical staining of CCL2 in untreated and WS treated tumors; (e) summarized data. There was a significant reduction (P < 0.05) in CCL2 expression in WS-treated tumors compared to untreated tumors as determined by Student's t-test. WS: Withania somnifera; CCL2: Chemokine (C-C motif) ligand 2