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![A review of nonsurgical facial rejuvenation](https://image.oaes.cc/f2686891-8426-44dd-b75b-1c7d26af1c13/3813.fig.2.jpg)
Figure 2. Skincare regimen in combination with pulsed-laser phototherapy [intense pulsed light (IPL)]. 46-year-old Fitzpatrick II Italian-portuguese female seeking perioral rejuvenation before (left) and after (right) a combination of daily skincare regimen (topical retinoid, vitamin C, and hydroquinone), hyaluronic acid filler to treat the upper lip rhytids, IPL for three sessions, microneedling to a 2 mm depth