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![Topical rapamycin for angiofibromas in patients with tuberous sclerosis: how does it work in clinical practice?](https://image.oaes.cc/c6867204-8610-42bb-b49c-9de48bb061c6/1785.fig.5.png)
Figure 5. Patient 12. (A) before CO2 laser and rapaymcin; (B) before CO2 laser and rapamycin close-up on the nose; (C) a couple of days after CO2 laser; (D) 3 months after CO2 laser and before rapamycin; (E) 3 months after CO2 laser close-up; (F) 3 months after CO2 laser close-up on the nose; (G) after CO2 laser and 9 months on rapamycin; (H) after CO2 laser and 9 months on rapamycin close-up nose