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![Topical rapamycin for angiofibromas in patients with tuberous sclerosis: how does it work in clinical practice?](https://image.oaes.cc/c6867204-8610-42bb-b49c-9de48bb061c6/1785.fig.3.png)
Figure 3. Patient 8. (A) 3 months after CO2 laser and before rapamycin; (B) 3 months after CO2 laser and before rapamycin close-up; (C) after 6 weeks on rapamycin; (D) after 9 months with topical rapamycin; (E) after 9 months on topical rapamycin close-up; (F) after 2 years