1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute Soochow University, Suzhou 215006, Jiangsu, China.
2The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, China.
3Department of Plastic and Reconstructive Surgery, Ninth People’s Hospital Affilicated to Medical School of Shanghai Jiao Tong University, Shanghai 200011, China.
Wen-Guo Cui1
,
Xin Zhao2
1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute Soochow University, Suzhou 215006, Jiangsu, China.
2The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, China.
3Department of Plastic and Reconstructive Surgery, Ninth People’s Hospital Affilicated to Medical School of Shanghai Jiao Tong University, Shanghai 200011, China.
Xin Zhao2
,
Yu-Guang Zhang3
1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute Soochow University, Suzhou 215006, Jiangsu, China.
2The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, China.
3Department of Plastic and Reconstructive Surgery, Ninth People’s Hospital Affilicated to Medical School of Shanghai Jiao Tong University, Shanghai 200011, China.
1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute Soochow University, Suzhou 215006, Jiangsu, China.
2The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, China.
3Department of Plastic and Reconstructive Surgery, Ninth People’s Hospital Affilicated to Medical School of Shanghai Jiao Tong University, Shanghai 200011, China.
Correspondence Address: Prof. Wen-Guo Cui, Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute Soochow University, Suzhou 215006, Jiangsu, China. E-mail: wgcui@suda.edu.cn
Received: 10 Feb 2016 | Accepted: 15 Feb 2016 | Published: 23 Mar 2016
Fountain of youth has always been the dream of mortals since the ancient time. Since ages ago, mortals have always been searching for ways to stay and look young. In the new millennia, retaining a youthful appearance is no longer a dream beyond reach. The advancement in medical technology, especially in the dermatological technology, has made the dream of youth possible.
The signs of aging often begin with the largest organ of human body, i.e. the skin. Facial wrinkles are the prominent sign of aging caused by facial volume loss under the skin, which will lead to skin sagging. The key to retain youth rely thus on prevention and treatment of wrinkles. As minimally invasive treatment, the emergence of intradermal fillers has excited the plastic surgeons. The injectable dermal fillers can be injected into the sagging skin to fill in the lost volume to rejuvenate facial appearance.
These intradermal fillers are divided into three categories which are biodegradable/non-permanent fillers, semi-permanent fillers, and permanent fillers. Biodegradable/non-permanent fillers include bovine collagen, porcine collagen, human collagen, hyaluronic acid and autologous fat and are often used to treat nasolabial folds. They are mainly from animal source and will degrade upon time (3-12 months) and thus can only be used as temporary filler. Semi-permanent fillers include poly-l-lactic acid and calcium hydroxylapatite. These fillers are biocompatible and do not show significant adverse effect when tested on patients. They will gradually degrade in vivo upon the formation of replacement tissues. Permanent fillers, e.g. the most frequently used silicone, is often used to treat severe facial volume loss. They are very advantageous for prosthetic reconstruction that requires excessive surgical intervention and low maintenance.
With the increase in demand for non-surgical dermatological enhancement, the world has placed a lot of focus in search of various intradermal fillers that can suite the patients’ demand. Young adult need it for youthful feature enhancement, middle aged adult need it for early prevention or volume restoration, while the mature need it for the delay and maintenance of aging related syndrome. Research is carried on progressively to search for optimal fillers that fulfil the requirement in effectiveness in treating facial aging, durability, no adverse effect on human body and cost effectiveness. Due to this ever increasing demand for better fillers, new formulation are created from time to time in short interval. Hybrid formulation that combines two or more fillers from different categories seems to be the trend of near future owing to its synergistic effects upon combination. Extra gadget such as radiofrequency devices also beneficial in enhancing the treatment efficiency, by prolonging the duration and reduce the number of injection. Minimally invasive treatment of facial aging using intradermal fillers is on its way!
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
Cite This Article
Editorial
Open Access
Biomaterials for facial aging
Wen-Guo Cui, ... Yu-Guang Zhang
How to Cite
Cui, W. G.; Zhao X.; Zhang Y. G. Biomaterials for facial aging. Plast. Aesthet. Res.2016, 3, 70-1. http://dx.doi.org/10.20517/2347-9264.2016.5
Download Citation
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click on download.
Export Citation File:
Type of Import
Tips on Downloading Citation
This feature enables you to download the bibliographic information (also called citation data, header data, or metadata) for the articles on our site.
Citation Manager File Format
Use the radio buttons to choose how to format the bibliographic data you're harvesting. Several citation manager formats are available, including EndNote and BibTex.
Type of Import
If you have citation management software installed on your computer your Web browser should be able to import metadata directly into your reference database.
Direct Import: When the Direct Import option is selected (the default state), a dialogue box will give you the option to Save or Open the downloaded citation data. Choosing Open will either launch your citation manager or give you a choice of applications with which to use the metadata. The Save option saves the file locally for later use.
Indirect Import: When the Indirect Import option is selected, the metadata is displayed and may be copied and pasted as needed.
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License (http://creativecommons.org/licenses/by-nc-sa/3.0/), which allows others to remix, tweak and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
Author Biographies
Dr. Wen-Guo Cui is a Professor in Orthopedic Institute at Soochow University. He received his PhD's degree in Materials Science (Biomaterials) from Southwest Jiaotong University in 2009. He then joined the Med-X Institute of SJTU until 2012, and Soochow University. After that he consecutively pursued research training at Harvard University until 2015. He now leads a multidisciplinary translational medical research using micro- or nanoscale biomaterials for tissue regeneration and drug delivery applications.
Comments must be written in English. Spam, offensive content, impersonation, and private information will not be permitted. If any
comment is reported and identified as inappropriate content by OAE staff, the comment will be removed without notice. If you have any
queries or need any help, please contact us at
support@oaepublish.com.
Open Access
Comments
Comments must be written in English. Spam, offensive content, impersonation, and private information will not be permitted. If any comment is reported and identified as inappropriate content by OAE staff, the comment will be removed without notice. If you have any queries or need any help, please contact us at support@oaepublish.com.