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![Intradermal fillers for minimally invasive treatment of facial aging](https://image.oaes.cc/9336634d-8d94-47df-b848-18d72cb6ea12/1344.fig.1.png)
Figure 1. Procedure protocol for injection of intradermal fillers for the treatment of facial aging. (i) The depth of needle insertion ranges from superficial to mid-dermis and is dependent on both wrinkle type and filler type; (ii) release of intradermal fillers through the needle; (iii) filler insertion results in smoothed wrinkles and the effect is long-lasting[31]