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![Tissue engineering using mesenchymal stem cell with periosteal wrap for bone defect repair in rabbits](https://image.oaes.cc/298bed05-637f-4533-a887-79578739f3c8/1241.fig.2.png)
Figure 2. Gross observations of the reconstruction of radius at 3 months after surgery. (a) Small amount of callus and fibrous‑like tissue in the interspaces between defect and human demineralized cancellous bone graft in Group 1; (b) callus formed in the defect repair by periosteum‑wrapped human demineralized cancellous bone graft in Group 2; (c) significant amount of callus and bony union filled in the defect repair with the human demineralized cancellous bone graft seeded with mesenchymal stem cells in Group 3; (d) complete bone healing in the defect repair by periosteum‑wrapped human demineralized cancellous bone graft seeded with bone marrow mesenchymal stem cells in Group 4