Special Topic

Topic: Latest Advances in Primary Immunodeficiency Diseases

A Special Topic of Rare Disease and Orphan Drugs Journal

ISSN 2771-2893 (Online)

Submission deadline: 30 Jun 2025

Guest Editor

Prof. Siobhan Burns

UCL Institute of Immunity & Transplantation, London, United Kingdom.

Special Topic Introduction

Primary Immunodeficiency Diseases (PID) are a group of rare, chronic disorders in which part of the body's immune system is missing or functions improperly. These diseases are usually inherited and can present in a variety of ways, often leading to increased susceptibility to infections, autoimmune disorders, and in some cases, an increased risk of cancer.

The significance of PIDs lies in their complex nature, which necessitates a multifaceted research approach. This Special Issue aims to encapsulate the latest advancements and comprehensive insights into PIDs, covering several critical areas:
● Genetic Research;
● Immunological Mechanisms;
● Clinical Phenotypes and Disease Spectrum;
● Diagnostic Technologies;
● Treatment Approaches;
● Patient Management and Care.

This Special Issue aims to provide a comprehensive overview of the current state of PID research, highlighting the advancements, challenges, and future directions. Through a deeper understanding of these multifaceted diseases, the goal is to improve diagnosis, management, and outcomes for individuals affected by PIDs.