Topic: Genomic Insights into the Etiology of Autism Spectrum Disorder in Children

Autism Spectrum Disorder (ASD) is a multifaceted neurodevelopmental condition marked by variability in social communication, behavior, and cognitive functions. Recent advancements in genomic research have shed light on the genetic underpinnings of ASD, offering promising pathways for understanding its complex etiology. This Special Issue aims to highlight cutting-edge research that delves into the genetic and epigenetic factors influencing ASD, with a particular focus on children.

We welcome contributions in the form of original research, comprehensive reviews, and case studies on topics including, but not limited to:

● Genetic Variants and Risk Genes: Identification and functional analysis of genetic variants linked to ASD susceptibility;

● Epigenetic Modifications: The role of DNA methylation, histone modifications, and non-coding RNAs in ASD;

● Gene-Environment Interactions: How environmental exposures influence genetic predisposition and contribute to ASD onset;

● Whole-Genome and Exome Sequencing: Advances in next-generation sequencing technologies for identifying novel mutations in ASD;

● Genetic Syndromes Associated with ASD: Insights into syndromic forms of autism and their genetic basis;

● Biomarkers and Diagnostics: Genomic markers for early diagnosis and prognosis of ASD in children;

● Therapeutic Implications: The potential of gene-based and personalized therapies in ASD management;

● Neurogenomics and Brain Development: Genomic studies linking gene expression to neurodevelopmental pathways in ASD;

● Inherited vs. De Novo Mutations: The role of inherited mutations and spontaneous genetic changes in ASD;

● Genetic Counseling: Implications of genomic findings for family planning and genetic counseling in ASD.