fig5

Electroencephalogram (EEG) network-level excitation-inhibition in <i>GRIN2B</i>-related neurodevelopmental disorders: a pilot case-control series

Figure 5. Functional E/I in source space in the range of 1-45 Hz. (A) shows fEl values in regions on source level per 11 bins. FEI was averaged across 68 patches of the Desikan Atlas and plotted for 6 regions. Red color shows significant regions for the GRIN2B patients while blue indicates significant regions for the TDC group. Grey areas show no significant results. Bootstrapping analyses were FDR corrected with 0.05. (B) shows an overview of region names. (C) shows the individual values of significant regions in source space per bin. Orange boxplots represent the GRIN2B patients, while black boxplots represent the TDC group with Δ indicating the average group difference with the P value of the significant regions. Higher values were found for the TDC group almost across all regions from 1.0-13.39 Hz. While the GRIN2B group only showed higher values for the left insula in bin 4.0-5.09 Hz.

Rare Disease and Orphan Drugs Journal
ISSN 2771-2893 (Online)
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