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![Cerebrovascular disorders and Fabry disease](https://image.oaes.cc/06339027-dc16-4ee1-bb8c-27f39b3af534/rdodj2051.fig.1.jpg)
Figure 1. A visual summary of the mechanism detailed in the section of pathophysiology. Image adapted by authors from ref[17,38]. tPA: Tissue plasmínogen activator; VCAM: vascular cell adhesion molecule; ICAM: intercellular adhesion molecule; Lyso-Gb3: globotriaosylsphingosine; ROS: reactive oxygen species; NO: nitric oxide; ANG: angiotensin; AT-1: angiotensin type 1 receptor; AT-2: angiotensin type 2 receptor; MPO: myeloperoxidase; RBC: red blood cells; WBC: white blood cells.