fig4
![Coenzyme Q10, Vitamin E and Polyvitamin B: an exploratory double-blind randomized cross-over study in Phelan-McDermid Syndrome](https://image.oaes.cc/c519aaf9-eef6-40f0-87b4-be13bf81843b/202308.fig.4.jpg)
Figure 4. Time x Treatment interaction for changes in (A) CGI-Improvement rated by clinicians; and (B) VAS “Restricted interests” rated by parents. For both variables, active compound produces significantly greater improvement when administered during Period II, but not during Period I. CGI-I scores: 1 = Very much improved, 2 = Much improved, 3 = Minimally improved, 4 = No change, 5 = Minimally worse, 6 = Very much worse.*P< 0.05.