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![COVID-19 and rare diseases: reflections and recommendations by the International Rare Diseases Research Consortium](https://image.oaes.cc/9640c6d1-94f1-47f0-9f4e-26c339edfc94/4471.fig.2.jpg)
Figure 2. Patient Advocacy Organizations reporting impacts of the COVID-19 pandemic on their organization. The PAOs reported that their members were negatively impacted by the pandemic as a result of decreased access to treatments, clinical trials, and access to diagnostic paths (A). In addition, PAOs reported challenges in operations resulting from increased demand for information/support, cancellation of fundraising events, and decreased participation and support for research activities (B). PAOs: Patient Advocacy Organizations.