fig1

Figure 1. (A) The typical pathological manifestations of glomerulus in Fabry disease under light microscope. Vacuole-like changes in the cytoplasm of podocytes and parietal epithelial cells were observed. (Periodic Acid-Schiff stain, ×400 times); (B) The typical pathological manifestations of glomerulus in Fabry disease under light microscope. A large number of Gb3 bodies were deposited in the cytoplasm of podocytes and parietal epithelial cells, and toluidine blue staining was observed. (×400 times); (C) Typical glomerular pathological manifestations of Fabry disease under electron microscope. A large number of “zebra bodies” formed by Gb3 deposition in the cytoplasm of podocytes and foot process segmental fusion.