fig1

Figure 1. lncRNAs participate in diverse cellular processes. (A) The ability of lncRNAs to bind DNA and protein complexes enables their transcription regulatory function, both inhibiting and enhancing gene transcription. (B) lncRNAs can facilitate the binding of splicing factors to regulate RNA splicing. (C) lncRNAs participate in the formation of nuclear paraspeckles. (D) mRNA stability can be regulated by diverse mechanisms involving lncRNA participation. (E) lncRNAs also bind miRNAs, avoiding the binding of miRNAs to target mRNAs. (F) lncRNAs are able to reduce or activate mRNA translation. (G) Some lncRNAs have small ORFs able to produce functional micropeptides. Created with BioRender.com.